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Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction
For over 2 decades preimplantation genetic testing (PGT) has been in clinical use to reduce the risk of miscarriage and genetic disease in patients with advanced maternal age and risk of transmitting disease. Recently developed methods of genome-wide genotyping and machine learning algorithms now of...
Autores principales: | Treff, Nathan R., Eccles, Jennifer, Lello, Lou, Bechor, Elan, Hsu, Jeffrey, Plunkett, Kathryn, Zimmerman, Raymond, Rana, Bhavini, Samoilenko, Artem, Hsu, Steven, Tellier, Laurent C. A. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915076/ https://www.ncbi.nlm.nih.gov/pubmed/31920964 http://dx.doi.org/10.3389/fendo.2019.00845 |
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