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Exosomal circHIPK3 Released from Hypoxia-Pretreated Cardiomyocytes Regulates Oxidative Damage in Cardiac Microvascular Endothelial Cells via the miR-29a/IGF-1 Pathway

BACKGROUND/AIMS: Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs that regulate gene expression in eukaryotes. Recently, exosomes from cardiomyocytes (CMs) have been found to facilitate cell proliferation and survival by transporting various bioactive molecules, including circRNA. H...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Zhao, Ranzun, Liu, Weiwei, Wang, Zhenglong, Rong, Jidong, Long, Xianping, Liu, Zhijiang, Ge, Junbo, Shi, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915129/
https://www.ncbi.nlm.nih.gov/pubmed/31885817
http://dx.doi.org/10.1155/2019/7954657