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Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis: The electron transfer hypothesis

INTRODUCTION: During evolution, some species including humans, monkeys and fruit bats lost the ability for ascorbic acid (AA) biosynthesis due to inactivation of the enzyme l-gulono-lactone oxidase (GLO) and subsequently became dependent on dietary vitamin C. There are four current hypotheses in rel...

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Detalles Bibliográficos
Autores principales: Hornung, Tabea C, Biesalski, Hans-Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915226/
https://www.ncbi.nlm.nih.gov/pubmed/31857900
http://dx.doi.org/10.1093/emph/eoz024