PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells

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p21-Activated kinase 4 (PAK4), a serine/threonine kinase, is purported to localize to podosomes: transient adhesive structures that degrade the extracellular matrix to facilitate rapid myeloid cell migration. We find that treatment of transforming growth factor β (TGF-β)-differentiated monocytic (TH...

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Detalles Bibliográficos
Autores principales: Foxall, Elizabeth, Staszowska, Adela, Hirvonen, Liisa M., Georgouli, Mirella, Ciccioli, Mariacristina, Rimmer, Alexander, Williams, Lynn, Calle, Yolanda, Moreno, Victoria Sanz, Cox, Susan, Jones, Gareth E., Wells, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915307/
https://www.ncbi.nlm.nih.gov/pubmed/31825823
http://dx.doi.org/10.1016/j.celrep.2019.11.016
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