PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells
p21-Activated kinase 4 (PAK4), a serine/threonine kinase, is purported to localize to podosomes: transient adhesive structures that degrade the extracellular matrix to facilitate rapid myeloid cell migration. We find that treatment of transforming growth factor β (TGF-β)-differentiated monocytic (TH...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915307/ https://www.ncbi.nlm.nih.gov/pubmed/31825823 http://dx.doi.org/10.1016/j.celrep.2019.11.016 |