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Intracellular Mycobacterium tuberculosis Exploits Multiple Host Nitrogen Sources during Growth in Human Macrophages

Nitrogen metabolism of Mycobacterium tuberculosis (Mtb) is crucial for the survival of this important pathogen in its primary human host cell, the macrophage, but little is known about the source(s) and their assimilation within this intracellular niche. Here, we have developed (15)N-flux spectral r...

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Detalles Bibliográficos
Autores principales: Borah, Khushboo, Beyß, Martin, Theorell, Axel, Wu, Huihai, Basu, Piyali, Mendum, Tom A., Nӧh, Katharina, Beste, Dany J.V., McFadden, Johnjoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915324/
https://www.ncbi.nlm.nih.gov/pubmed/31825837
http://dx.doi.org/10.1016/j.celrep.2019.11.037