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Mature miR-99a Upregulation in the Amniotic Fluid Samples from Female Fetus Down Syndrome Pregnancies: A Pilot Study

Background and Objective: Although Down syndrome is the most frequent aneuploidy, its pathogenic molecular mechanisms are not yet fully understood. The aim of our study is to quantify—by qRT-PCR—the expression levels of both the mature forms and the pri-miRNAs of the microRNAs resident on chromosome...

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Detalles Bibliográficos
Autores principales: Vizitiu, Anda-Cornelia, Stambouli, Danae, Pavel, Anca-Gabriela, Muresan, Maria-Cezara, Anastasiu, Diana Maria, Bejinar, Cristina, Alexa, Anda, Marian, Catalin, Sirbu, Ioan Ovidiu, Sima, Laurentiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915350/
https://www.ncbi.nlm.nih.gov/pubmed/31703316
http://dx.doi.org/10.3390/medicina55110728