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A muscular hypotonia-associated STIM1 mutant at R429 induces abnormalities in intracellular Ca(2+) movement and extracellular Ca(2+) entry in skeletal muscle

Stromal interaction molecule 1 (STIM1) mediates extracellular Ca(2+) entry into the cytosol through a store-operated Ca(2+) entry (SOCE) mechanism, which is involved in the physiological functions of various tissues, including skeletal muscle. STIM1 is also associated with skeletal muscle diseases,...

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Detalles Bibliográficos
Autores principales: Choi, Jun Hee, Huang, Mei, Hyun, Changdo, Oh, Mi Ri, Lee, Keon Jin, Cho, Chung-Hyun, Lee, Eun Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915709/
https://www.ncbi.nlm.nih.gov/pubmed/31844136
http://dx.doi.org/10.1038/s41598-019-55745-z