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A muscular hypotonia-associated STIM1 mutant at R429 induces abnormalities in intracellular Ca(2+) movement and extracellular Ca(2+) entry in skeletal muscle
Stromal interaction molecule 1 (STIM1) mediates extracellular Ca(2+) entry into the cytosol through a store-operated Ca(2+) entry (SOCE) mechanism, which is involved in the physiological functions of various tissues, including skeletal muscle. STIM1 is also associated with skeletal muscle diseases,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915709/ https://www.ncbi.nlm.nih.gov/pubmed/31844136 http://dx.doi.org/10.1038/s41598-019-55745-z |