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Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver

Spaceflight has several detrimental effects on the physiology of astronauts, many of which are recapitulated in rodent models. Mouse studies performed on the Space Shuttle showed disruption of lipid metabolism in liver. However, given that these animals were not sacrificed on-orbit and instead retur...

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Detalles Bibliográficos
Autores principales: Beheshti, Afshin, Chakravarty, Kaushik, Fogle, Homer, Fazelinia, Hossein, Silveira, Willian A. da, Boyko, Valery, Polo, San-Huei Lai, Saravia-Butler, Amanda M., Hardiman, Gary, Taylor, Deanne, Galazka, Jonathan M., Costes, Sylvain V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915713/
https://www.ncbi.nlm.nih.gov/pubmed/31844325
http://dx.doi.org/10.1038/s41598-019-55869-2