Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action

Antimicrobial peptides (AMPs) are key effectors of the innate immune system and promising therapeutic agents. Yet, knowledge on how to design AMPs with minimal cross-resistance to human host-defense peptides remains limited. Here, we systematically assess the resistance determinants of Escherichia c...

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Detalles Bibliográficos
Autores principales: Kintses, Bálint, Jangir, Pramod K., Fekete, Gergely, Számel, Mónika, Méhi, Orsolya, Spohn, Réka, Daruka, Lejla, Martins, Ana, Hosseinnia, Ali, Gagarinova, Alla, Kim, Sunyoung, Phanse, Sadhna, Csörgő, Bálint, Györkei, Ádám, Ari, Eszter, Lázár, Viktória, Nagy, István, Babu, Mohan, Pál, Csaba, Papp, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915728/
https://www.ncbi.nlm.nih.gov/pubmed/31844052
http://dx.doi.org/10.1038/s41467-019-13618-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915728/
https://www.ncbi.nlm.nih.gov/pubmed/31844052
http://dx.doi.org/10.1038/s41467-019-13618-z

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