Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials

Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence. Epigenetic dysregulation is often linked to human disease, notably cancer. With the development of various drugs targeting epigenetic regulator...

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Detalles Bibliográficos
Autores principales: Cheng, Yuan, He, Cai, Wang, Manni, Ma, Xuelei, Mo, Fei, Yang, Shengyong, Han, Junhong, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915746/
https://www.ncbi.nlm.nih.gov/pubmed/31871779
http://dx.doi.org/10.1038/s41392-019-0095-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915746/
https://www.ncbi.nlm.nih.gov/pubmed/31871779
http://dx.doi.org/10.1038/s41392-019-0095-0

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