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Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials
Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence. Epigenetic dysregulation is often linked to human disease, notably cancer. With the development of various drugs targeting epigenetic regulator...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915746/ https://www.ncbi.nlm.nih.gov/pubmed/31871779 http://dx.doi.org/10.1038/s41392-019-0095-0 |