Cargando…

Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency

In contrast to conventional human pluripotent stem cells (hPSCs) that are related to post-implantation embryo stages, naive hPSCs exhibit features of pre-implantation epiblast. Naive hPSCs are established by resetting conventional hPSCs, or are derived from dissociated embryo inner cell masses. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Bredenkamp, Nicholas, Yang, Jian, Clarke, James, Stirparo, Giuliano Giuseppe, von Meyenn, Ferdinand, Dietmann, Sabine, Baker, Duncan, Drummond, Rosalind, Ren, Yongming, Li, Dongwei, Wu, Chuman, Rostovskaya, Maria, Eminli-Meissner, Sarah, Smith, Austin, Guo, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915845/
https://www.ncbi.nlm.nih.gov/pubmed/31708477
http://dx.doi.org/10.1016/j.stemcr.2019.10.009