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Drug Discovery Platform Targeting M. tuberculosis with Human Embryonic Stem Cell-Derived Macrophages

A major limitation in anti-tuberculosis drug screening is the lack of reliable and scalable models for homogeneous human primary macrophage cells of non-cancer origin. Here we report a modified protocol for generating homogeneous populations of macrophage-like cells from human embryonic stem cells....

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Detalles Bibliográficos
Autores principales: Han, Hyo-Won, Seo, Hyang-Hee, Jo, Hye-Yeong, Han, Hyeong-jun, Falcão, Virgínia C.A., Delorme, Vincent, Heo, Jinyeong, Shum, David, Choi, Jang-Hoon, Lee, Jin-Moo, Lee, Seung Hun, Heo, Hye-Ryeon, Hong, Seok-Ho, Park, Mi-Hyun, Thimmulappa, Rajesh K., Kim, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915848/
https://www.ncbi.nlm.nih.gov/pubmed/31680058
http://dx.doi.org/10.1016/j.stemcr.2019.10.002