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Drug Discovery Platform Targeting M. tuberculosis with Human Embryonic Stem Cell-Derived Macrophages
A major limitation in anti-tuberculosis drug screening is the lack of reliable and scalable models for homogeneous human primary macrophage cells of non-cancer origin. Here we report a modified protocol for generating homogeneous populations of macrophage-like cells from human embryonic stem cells....
Autores principales: | Han, Hyo-Won, Seo, Hyang-Hee, Jo, Hye-Yeong, Han, Hyeong-jun, Falcão, Virgínia C.A., Delorme, Vincent, Heo, Jinyeong, Shum, David, Choi, Jang-Hoon, Lee, Jin-Moo, Lee, Seung Hun, Heo, Hye-Ryeon, Hong, Seok-Ho, Park, Mi-Hyun, Thimmulappa, Rajesh K., Kim, Jung-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915848/ https://www.ncbi.nlm.nih.gov/pubmed/31680058 http://dx.doi.org/10.1016/j.stemcr.2019.10.002 |
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