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Deconvoluting the diversity of within-host pathogen strains in a multi-locus sequence typing framework

BACKGROUND: Bacterial pathogens exhibit an impressive amount of genomic diversity. This diversity can be informative of evolutionary adaptations, host-pathogen interactions, and disease transmission patterns. However, capturing this diversity directly from biological samples is challenging. RESULTS:...

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Detalles Bibliográficos
Autores principales: Gan, Guo Liang, Willie, Elijah, Chauve, Cedric, Chindelevitch, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915855/
https://www.ncbi.nlm.nih.gov/pubmed/31842753
http://dx.doi.org/10.1186/s12859-019-3204-8