Recovering rearranged cancer chromosomes from karyotype graphs

BACKGROUND: Many cancer genomes are extensively rearranged with highly aberrant chromosomal karyotypes. Structural and copy number variations in cancer genomes can be determined via abnormal mapping of sequenced reads to the reference genome. Recently it became possible to reconcile both of these ty...

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Detalles Bibliográficos
Autores principales: Aganezov, Sergey, Zban, Ilya, Aksenov, Vitaly, Alexeev, Nikita, Schatz, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915857/
https://www.ncbi.nlm.nih.gov/pubmed/31842730
http://dx.doi.org/10.1186/s12859-019-3208-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915857/
https://www.ncbi.nlm.nih.gov/pubmed/31842730
http://dx.doi.org/10.1186/s12859-019-3208-4

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