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Region-specific blood–brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease

BACKGROUND: Research into amisulpride use in Alzheimer’s disease (AD) implicates blood–brain barrier (BBB) dysfunction in antipsychotic sensitivity. Research into BBB transporters has been mainly directed towards the ABC superfamily, however, solute carrier (SLC) function in AD has not been widely s...

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Detalles Bibliográficos
Autores principales: Sekhar, Gayathri Nair, Fleckney, Alice L., Boyanova, Sevda Tomova, Rupawala, Huzefa, Lo, Rachel, Wang, Hao, Farag, Doaa B., Rahman, Khondaker Miraz, Broadstock, Martin, Reeves, Suzanne, Thomas, Sarah Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915870/
https://www.ncbi.nlm.nih.gov/pubmed/31842924
http://dx.doi.org/10.1186/s12987-019-0158-1