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Simulation and minimization: technical advances for factorial experiments designed to optimize clinical interventions
BACKGROUND: The Multiphase Optimization Strategy (MOST) is designed to maximize the impact of clinical healthcare interventions, which are typically multicomponent and increasingly complex. MOST often relies on factorial experiments to identify which components of an intervention are most effective,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915895/ https://www.ncbi.nlm.nih.gov/pubmed/31842765 http://dx.doi.org/10.1186/s12874-019-0883-9 |