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SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish

OBJECTIVE: Neural tube defects (NTDs) are the most serious and common birth defects in the clinic. The SRY-related HMG box B1 (SoxB1) gene family has been implicated in different processes of early embryogenesis. Sox19b is a maternally expressed gene in the SoxB1 family that is found in the region o...

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Detalles Bibliográficos
Autores principales: Li, Xian, Zhou, Wenjuan, Li, Xinyue, Gao, Ming, Ji, Shufang, Tian, Wenyu, Ji, Guangyu, Du, Jingyi, Hao, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915949/
https://www.ncbi.nlm.nih.gov/pubmed/31842983
http://dx.doi.org/10.1186/s13287-019-1495-3