Severe but not moderate hyperoxia of newborn mice causes an emphysematous lung phenotype in adulthood without persisting oxidative stress and inflammation

BACKGROUND: Preterm newborns typically require supplemental oxygen but hyperoxic conditions also damage the premature lung. Oxygen-induced lung damages are mainly studied in newborn mouse models using oxygen concentrations above 75% and looking at short-term effects. Therefore, we aimed at the inves...

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Detalles Bibliográficos
Autores principales: Kindermann, Anke, Binder, Leonore, Baier, Jan, Gündel, Beate, Simm, Andreas, Haase, Roland, Bartling, Babett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915952/
https://www.ncbi.nlm.nih.gov/pubmed/31842840
http://dx.doi.org/10.1186/s12890-019-0993-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915952/
https://www.ncbi.nlm.nih.gov/pubmed/31842840
http://dx.doi.org/10.1186/s12890-019-0993-5

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