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Severe but not moderate hyperoxia of newborn mice causes an emphysematous lung phenotype in adulthood without persisting oxidative stress and inflammation
BACKGROUND: Preterm newborns typically require supplemental oxygen but hyperoxic conditions also damage the premature lung. Oxygen-induced lung damages are mainly studied in newborn mouse models using oxygen concentrations above 75% and looking at short-term effects. Therefore, we aimed at the inves...
Autores principales: | Kindermann, Anke, Binder, Leonore, Baier, Jan, Gündel, Beate, Simm, Andreas, Haase, Roland, Bartling, Babett |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915952/ https://www.ncbi.nlm.nih.gov/pubmed/31842840 http://dx.doi.org/10.1186/s12890-019-0993-5 |
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