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Guidelines for benchmarking of optimization-based approaches for fitting mathematical models
Insufficient performance of optimization-based approaches for the fitting of mathematical models is still a major bottleneck in systems biology. In this article, the reasons and methodological challenges are summarized as well as their impact in benchmark studies. Important aspects for achieving an...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915982/ https://www.ncbi.nlm.nih.gov/pubmed/31842943 http://dx.doi.org/10.1186/s13059-019-1887-9 |