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Guidelines for benchmarking of optimization-based approaches for fitting mathematical models

Insufficient performance of optimization-based approaches for the fitting of mathematical models is still a major bottleneck in systems biology. In this article, the reasons and methodological challenges are summarized as well as their impact in benchmark studies. Important aspects for achieving an...

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Detalles Bibliográficos
Autor principal: Kreutz, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915982/
https://www.ncbi.nlm.nih.gov/pubmed/31842943
http://dx.doi.org/10.1186/s13059-019-1887-9