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In vitro anti-malarial efficacy of chalcones: cytotoxicity profile, mechanism of action and their effect on erythrocytes

BACKGROUND: Malaria extensively leads to mortality and morbidity in endemic regions, and the emergence of drug resistant parasites is alarming. Plant derived synthetic pharmaceutical compounds are found to be a foremost research to obtain diverse range of potent leads. Amongst them, the chalcone sca...

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Detalles Bibliográficos
Autores principales: Sinha, Shweta, Batovska, Daniela I., Medhi, Bikash, Radotra, B. D., Bhalla, Ashish, Markova, Nadezhda, Sehgal, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916019/
https://www.ncbi.nlm.nih.gov/pubmed/31842914
http://dx.doi.org/10.1186/s12936-019-3060-z