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Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer’s disease

BACKGROUND: Soluble epoxide hydrolase (sEH) is a bifunctional enzyme with COOH-terminal hydrolase and NH2-terminal lipid phosphatase activities. It is expressed in various cell types in the brain and is involved in the pathogenesis of inflammatory and neurodegenerative diseases. Alzheimer’s disease...

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Detalles Bibliográficos
Autores principales: Lee, Hsueh-Te, Lee, Kuan-I, Chen, Chia-Hui, Lee, Tzong-Shyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916033/
https://www.ncbi.nlm.nih.gov/pubmed/31847859
http://dx.doi.org/10.1186/s12974-019-1635-9