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Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer’s disease
BACKGROUND: Soluble epoxide hydrolase (sEH) is a bifunctional enzyme with COOH-terminal hydrolase and NH2-terminal lipid phosphatase activities. It is expressed in various cell types in the brain and is involved in the pathogenesis of inflammatory and neurodegenerative diseases. Alzheimer’s disease...
Autores principales: | Lee, Hsueh-Te, Lee, Kuan-I, Chen, Chia-Hui, Lee, Tzong-Shyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916033/ https://www.ncbi.nlm.nih.gov/pubmed/31847859 http://dx.doi.org/10.1186/s12974-019-1635-9 |
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