HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA

BACKGROUND: The HERV-K (HML-2) viruses are the youngest of the human endogenous retroviruses. They are present as several almost complete proviral copies and numerous fragments in the human genome. Many HERV-K proviruses express a regulatory protein Rec, which binds to an element present in HERV-K m...

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Detalles Bibliográficos
Autores principales: Gray, Laurie R., Jackson, Rachel E., Jackson, Patrick E. H., Bekiranov, Stefan, Rekosh, David, Hammarskjöld, Marie-Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916052/
https://www.ncbi.nlm.nih.gov/pubmed/31842941
http://dx.doi.org/10.1186/s12977-019-0505-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916052/
https://www.ncbi.nlm.nih.gov/pubmed/31842941
http://dx.doi.org/10.1186/s12977-019-0505-y

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