FIREVAT: finding reliable variants without artifacts in human cancer samples using etiologically relevant mutational signatures

BACKGROUND: Accurate identification of real somatic variants is a primary part of cancer genome studies and precision oncology. However, artifacts introduced in various steps of sequencing obfuscate confidence in variant calling. Current computational approaches to variant filtering involve intensiv...

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Detalles Bibliográficos
Autores principales: Kim, Hyunbin, Lee, Andy Jinseok, Lee, Jongkeun, Chun, Hyonho, Ju, Young Seok, Hong, Dongwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916105/
https://www.ncbi.nlm.nih.gov/pubmed/31847917
http://dx.doi.org/10.1186/s13073-019-0695-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916105/
https://www.ncbi.nlm.nih.gov/pubmed/31847917
http://dx.doi.org/10.1186/s13073-019-0695-x

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