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FIREVAT: finding reliable variants without artifacts in human cancer samples using etiologically relevant mutational signatures
BACKGROUND: Accurate identification of real somatic variants is a primary part of cancer genome studies and precision oncology. However, artifacts introduced in various steps of sequencing obfuscate confidence in variant calling. Current computational approaches to variant filtering involve intensiv...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916105/ https://www.ncbi.nlm.nih.gov/pubmed/31847917 http://dx.doi.org/10.1186/s13073-019-0695-x |