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FcγRIIIa receptor polymorphism influences NK cell mediated ADCC activity against HIV

BACKGROUND: HIV-specific Antibody Dependent Cell Cytotoxicity (ADCC) has shown to be important in HIV control and resistance. The ADCC is mediated primarily by natural killer cell activated through the binding of FcγRIIIa receptor to the Fc portion of antibody bound to the antigen expressed on the i...

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Detalles Bibliográficos
Autores principales: Talathi, Sneha Pramod, Shaikh, Nawaj Najir, Pandey, Sudhanshu Shekhar, Saxena, Vandana Ashish, Mamulwar, Megha Sunil, Thakar, Madhuri Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916223/
https://www.ncbi.nlm.nih.gov/pubmed/31842762
http://dx.doi.org/10.1186/s12879-019-4674-z