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Aβ oligomers trigger and accelerate Aβ seeding
Aggregation of amyloid‐β (Aβ) that leads to the formation of plaques in Alzheimer's disease (AD) occurs through the stepwise formation of oligomers and fibrils. An earlier onset of aggregation is obtained upon intracerebral injection of Aβ‐containing brain homogenate into human APP transgenic m...
Autores principales: | Katzmarski, Natalie, Ziegler‐Waldkirch, Stephanie, Scheffler, Nina, Witt, Christian, Abou‐Ajram, Claudia, Nuscher, Brigitte, Prinz, Marco, Haass, Christian, Meyer‐Luehmann, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916291/ https://www.ncbi.nlm.nih.gov/pubmed/31099449 http://dx.doi.org/10.1111/bpa.12734 |
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