Identification of cysteine thiol‐based linkages in ADAMTS13 in support of a non‐proteolytic regulation of von Willebrand factor

BACKGROUND: ADAMTS13, a plasma metalloprotease, cleaves von Willebrand factor (VWF) to regulate its function. Additionally, ADAMTS13 is thought to regulate lateral association of VWF multimers to form fibrillar structures through its free thiols. OBJECTIVE: The purpose of the present study is to obt...

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Detalles Bibliográficos
Autores principales: Rottensteiner, Hanspeter, Seyfried, Birgit K., Kaufmann, Stefan, Fiedler, Christian, Dong, Jing‐Fei, Zheng, X. Long, Plaimauer, Barbara, Scheiflinger, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
THROMBOSIS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916347/
https://www.ncbi.nlm.nih.gov/pubmed/31393047
http://dx.doi.org/10.1111/jth.14602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916347/
https://www.ncbi.nlm.nih.gov/pubmed/31393047
http://dx.doi.org/10.1111/jth.14602

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