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Loss of Single‐Domain Function in a Modular Assembly Line Alters the Size and Shape of a Complex Polyketide
The structural wealth of complex polyketide metabolites produced by bacteria results from intricate, highly evolved biosynthetic programs of modular assembly lines, in which the number of modules defines the size of the backbone, and the domain composition controls the degree of functionalization. W...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916388/ https://www.ncbi.nlm.nih.gov/pubmed/31595618 http://dx.doi.org/10.1002/anie.201911315 |