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Disruption of circadian rhythm by alternating light‐dark cycles aggravates atherosclerosis development in APOE*3‐Leiden.CETP mice

Disruption of circadian rhythm by means of shift work has been associated with cardiovascular disease in humans. However, causality and underlying mechanisms have not yet been established. In this study, we exposed hyperlipidemic APOE*3‐Leiden.CETP mice to either regular light‐dark cycles, weekly 6 ...

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Detalles Bibliográficos
Autores principales: Schilperoort, Maaike, van den Berg, Rosa, Bosmans, Laura A., van Os, Bram W., Dollé, Martijn E. T., Smits, Noortje A. M., Guichelaar, Teun, van Baarle, Debbie, Koemans, Lotte, Berbée, Jimmy F. P., Deboer, Tom, Meijer, Johanna H., de Vries, Margreet R., Vreeken, Dianne, van Gils, Janine M., Willems van Dijk, Ko, van Kerkhof, Linda W. M., Lutgens, Esther, Biermasz, Nienke R., Rensen, Patrick C. N., Kooijman, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916424/
https://www.ncbi.nlm.nih.gov/pubmed/31599473
http://dx.doi.org/10.1111/jpi.12614