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Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their progeny past the pluripotency stage

BACKGROUND: Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or inducible variants of these recombinases are expressed under the control of either lineage-specific or ubiquitous promoters. However, t...

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Detalles Bibliográficos
Autores principales: Kuzmin, Andrey A., Ermakova, Veronika V., Sinenko, Sergey A., Ponomartsev, Sergey V., Starkova, Tatiana Y., Skvortsova, Elena V., Cherepanova, Olga, Tomilin, Alexey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916430/
https://www.ncbi.nlm.nih.gov/pubmed/31843009
http://dx.doi.org/10.1186/s13287-019-1520-6