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Modeling appendicular skeletal cartilage development with modified high-density micromass cultures of adult human bone marrow-derived mesenchymal progenitor cells

BACKGROUND: Animal cell-based systems have been critical tools in understanding tissue development and physiology, but they are less successful in more practical tasks, such as predicting human toxicity to pharmacological or environmental factors, in which the congruence between in vitro and clinica...

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Detalles Bibliográficos
Autores principales: Pirosa, Alessandro, Clark, Karen L., Tan, Jian, Yu, Shuting, Yang, Yuanheng, Tuan, Rocky S., Alexander, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916440/
https://www.ncbi.nlm.nih.gov/pubmed/31842986
http://dx.doi.org/10.1186/s13287-019-1505-5