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Modeling appendicular skeletal cartilage development with modified high-density micromass cultures of adult human bone marrow-derived mesenchymal progenitor cells
BACKGROUND: Animal cell-based systems have been critical tools in understanding tissue development and physiology, but they are less successful in more practical tasks, such as predicting human toxicity to pharmacological or environmental factors, in which the congruence between in vitro and clinica...
Autores principales: | Pirosa, Alessandro, Clark, Karen L., Tan, Jian, Yu, Shuting, Yang, Yuanheng, Tuan, Rocky S., Alexander, Peter G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916440/ https://www.ncbi.nlm.nih.gov/pubmed/31842986 http://dx.doi.org/10.1186/s13287-019-1505-5 |
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