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Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules

T-tubules are invaginations of the lateral membrane of striated muscle cells that provide a large surface for ion channels and signaling proteins, thereby supporting excitation–contraction coupling. T-tubules are often remodeled in heart failure. To better understand the electrical behavior of T-tub...

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Detalles Bibliográficos
Autores principales: Vermij, Sarah Helena, Abriel, Hugues, Kucera, Jan Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916517/
https://www.ncbi.nlm.nih.gov/pubmed/31920695
http://dx.doi.org/10.3389/fphys.2019.01487