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Cell‐of‐origin determined by both gene expression profiling and immunohistochemistry is the strongest predictor of survival in patients with diffuse large B‐cell lymphoma

The tumor cells in diffuse large B‐cell lymphomas (DLBCL) are considered to originate from germinal center derived B‐cells (GCB) or activated B‐cells (ABC). Gene expression profiling (GEP) is preferably used to determine the cell of origin (COO). However, GEP is not widely applied in clinical practi...

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Detalles Bibliográficos
Autores principales: Abdulla, Maysaa, Hollander, Peter, Pandzic, Tatjana, Mansouri, Larry, Ednersson, Susanne Bram, Andersson, Per‐Ola, Hultdin, Magnus, Fors, Maja, Erlanson, Martin, Degerman, Sofie, Petersen, Helga Munch, Asmar, Fazila, Grønbæk, Kirsten, Enblad, Gunilla, Cavelier, Lucia, Rosenquist, Richard, Amini, Rose‐Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916573/
https://www.ncbi.nlm.nih.gov/pubmed/31659781
http://dx.doi.org/10.1002/ajh.25666