CDH1 (E-Cadherin) Mutation and Gastric Cancer: Genetics, Molecular Mechanisms and Guidelines for Management

INTRODUCTION: Germline mutation in CDH1 (E-cadherin) tumor suppressor gene is associated with hereditary diffuse gastric cancer (HDGC) and lobular breast cancers (LBC). E-Cadherin protein is necessary for physiological signaling pathways, such as cell proliferation, maintenance of cell adhesion, cel...

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Detalles Bibliográficos
Autor principal: Shenoy, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916690/
https://www.ncbi.nlm.nih.gov/pubmed/31853199
http://dx.doi.org/10.2147/CMAR.S208818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916690/
https://www.ncbi.nlm.nih.gov/pubmed/31853199
http://dx.doi.org/10.2147/CMAR.S208818

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