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p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis
SESTRINs (SESN1-3) are proteins encoded by an evolutionarily conserved gene family that plays an important role in the regulation of cell viability and metabolism in response to stress. Many of the effects of SESTRINs are mediated by negative and positive regulation of mechanistic target of rapamyci...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916756/ https://www.ncbi.nlm.nih.gov/pubmed/31857853 http://dx.doi.org/10.18632/oncotarget.27367 |