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p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis

SESTRINs (SESN1-3) are proteins encoded by an evolutionarily conserved gene family that plays an important role in the regulation of cell viability and metabolism in response to stress. Many of the effects of SESTRINs are mediated by negative and positive regulation of mechanistic target of rapamyci...

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Detalles Bibliográficos
Autores principales: Ding, Boxiao, Haidurov, Alexander, Chawla, Ayesha, Parmigiani, Anita, van de Kamp, Gerarda, Dalina, Alexandra, Yuan, Fang, Lee, Jun Hee, Chumakov, Peter M., Grossman, Steven R., Budanov, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916756/
https://www.ncbi.nlm.nih.gov/pubmed/31857853
http://dx.doi.org/10.18632/oncotarget.27367