APP‐derived peptides reflect neurodegeneration in frontotemporal dementia

OBJECTIVE: We aimed to investigate the relationship between cerebrospinal fluid levels (CSF) of amyloid precursor protein (APP)‐derived peptides related to the amyloidogenic pathway, cortical thickness, neuropsychological performance, and cortical gene expression profiles in frontotemporal lobar deg...

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Detalles Bibliográficos
Autores principales: Illán‐Gala, Ignacio, Pegueroles, Jordi, Montal, Victor, Alcolea, Daniel, Vilaplana, Eduard, Bejanin, Alexandre, Borrego‐Écija, Sergi, Sampedro, Frederic, Subirana, Andrea, Sánchez‐Saudinós, María‐Belén, Rojas‐García, Ricard, Vanderstichele, Hugo, Blesa, Rafael, Clarimón, Jordi, Antonell, Anna, Lladó, Albert, Sánchez‐Valle, Raquel, Fortea, Juan, Lleó, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917306/
https://www.ncbi.nlm.nih.gov/pubmed/31789459
http://dx.doi.org/10.1002/acn3.50948