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Dexmedetomidine attenuates P2X4 and NLRP3 expression in the spine of rats with diabetic neuropathic pain

PURPOSE: To evaluate the effects of Dexmedetomidine (Dex) on spinal pathology and inflammatory factor in a rat model of Diabetic neuropathic pain (DNP). METHODS: The rats were divided into 3 groups (eight in each group): normal group (N group), diabetic neuropathic pain model group (DNP group), and...

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Detalles Bibliográficos
Autores principales: Kang, Liu, Yayi, Huang, Fang, Zhou, Bo, Zhao, Zhongyuan, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917476/
https://www.ncbi.nlm.nih.gov/pubmed/31859818
http://dx.doi.org/10.1590/s0102-865020190110000005