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B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments

Antibody production depends on B cell internalization and presentation of antigens to helper T cells. To acquire antigens displayed by antigen-presenting cells, B cells form immune synapses and extract antigens by the mechanical activity of the acto-myosin cytoskeleton. While cytoskeleton organizati...

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Detalles Bibliográficos
Autores principales: Roper, Sophie I, Wasim, Laabiah, Malinova, Dessislava, Way, Michael, Cox, Susan, Tolar, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917489/
https://www.ncbi.nlm.nih.gov/pubmed/31815664
http://dx.doi.org/10.7554/eLife.48093