Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade

Coronaries are essential for myocardial growth and heart function. Notch is crucial for mouse embryonic angiogenesis, but its role in coronary development remains uncertain. We show Jag1, Dll4 and activated Notch1 receptor expression in sinus venosus (SV) endocardium. Endocardial Jag1 removal blocks...

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Detalles Bibliográficos
Autores principales: Travisano, Stanislao Igor, Oliveira, Vera Lucia, Prados, Belén, Grego-Bessa, Joaquim, Piñeiro-Sabarís, Rebeca, Bou, Vanesa, Gómez, Manuel J, Sánchez-Cabo, Fátima, MacGrogan, Donal, de la Pompa, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917494/
https://www.ncbi.nlm.nih.gov/pubmed/31789590
http://dx.doi.org/10.7554/eLife.49977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917494/
https://www.ncbi.nlm.nih.gov/pubmed/31789590
http://dx.doi.org/10.7554/eLife.49977

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