Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo

Macrophages are heterogeneous leukocytes regulated in a tissue- and disease-specific context. While in vitro macrophage models have been used to study diseases empirically, a systematic analysis of the transcriptome thereof is lacking. Here, we acquired gene expression data from eight commonly-used...

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Detalles Bibliográficos
Autores principales: Chen, Hung-Jen, Li Yim, Andrew Y. F., Griffith, Guillermo R., de Jonge, Wouter J., Mannens, Marcel M. A. M., Ferrero, Enrico, Henneman, Peter, de Winther, Menno P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917623/
https://www.ncbi.nlm.nih.gov/pubmed/31921150
http://dx.doi.org/10.3389/fimmu.2019.02887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917623/
https://www.ncbi.nlm.nih.gov/pubmed/31921150
http://dx.doi.org/10.3389/fimmu.2019.02887

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