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High Content Solid Dispersions for Dose Window Extension: A Basis for Design Flexibility in Fused Deposition Modelling

PURPOSE: This study uses high drug content solid dispersions for dose window extension beyond current demonstrations using fused deposition modelling (FDM) to; i) accommodate pharmaceutically relevant doses of drugs of varying potencies at acceptable dosage form sizes and ii) enable enhanced dose fl...

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Detalles Bibliográficos
Autores principales: Govender, Rydvikha, Abrahmsén-Alami, Susanna, Folestad, Staffan, Larsson, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917630/
https://www.ncbi.nlm.nih.gov/pubmed/31848730
http://dx.doi.org/10.1007/s11095-019-2720-6