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Hematopoietic Cell Transplantation for MHC Class II Deficiency

Major histocompatibility complex (MHC) class II deficiency is a rare and fatal primary combined immunodeficiency. It affects both marrow-derived cells and thymic epithelium, leading to impaired antigen presentation by antigen presenting cells and delayed and incomplete maturation of CD4+ lymphocyte...

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Detalles Bibliográficos
Autores principales: Lum, Su Han, Neven, Benedicte, Slatter, Mary A., Gennery, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917634/
https://www.ncbi.nlm.nih.gov/pubmed/31921728
http://dx.doi.org/10.3389/fped.2019.00516