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Drug-Induced Liver Injury: Biomarkers, Requirements, Candidates, and Validation
The hepatotoxicity of drugs is the main cause of drug withdrawal from the pharmaceutical market and interruption of the development of new molecules. Biomarkers are useful in several situations. In case of suspected drug-induced liver injury (DILI), biomarkers can be used to confirm liver damage, it...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917655/ https://www.ncbi.nlm.nih.gov/pubmed/31920666 http://dx.doi.org/10.3389/fphar.2019.01482 |