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Drug-Induced Liver Injury: Biomarkers, Requirements, Candidates, and Validation

The hepatotoxicity of drugs is the main cause of drug withdrawal from the pharmaceutical market and interruption of the development of new molecules. Biomarkers are useful in several situations. In case of suspected drug-induced liver injury (DILI), biomarkers can be used to confirm liver damage, it...

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Detalles Bibliográficos
Autores principales: Meunier, Lucy, Larrey, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917655/
https://www.ncbi.nlm.nih.gov/pubmed/31920666
http://dx.doi.org/10.3389/fphar.2019.01482