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High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia

Neonatal hypoxic-ischemic (HI) encephalopathy is a severe disease for which there is currently no curative treatment. Recent evidence suggests that high-mobility group box 1 (HMGB1) protein can promote neuroinflammation after stroke in adult rodents, but its role in perinatal hypoxic-ischemic brain...

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Detalles Bibliográficos
Autores principales: Sun, Yanyan, Hei, Mingyan, Fang, Zhihui, Tang, Zhen, Wang, Bo, Hu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917666/
https://www.ncbi.nlm.nih.gov/pubmed/31920543
http://dx.doi.org/10.3389/fncel.2019.00506